The triple workday faced by women entrepreneurs involves balancing multiple responsibilities—household chores, childcare, and business duties—creating significant challenges that impact their quality of life and mental health, particularly leading to burnout. Female entrepreneurs also encounter gender-related barriers, sexism, difficulties accessing credit, and limited entrepreneurial training and support networks. This study aims to analyze the relationship between the triple workday and burnout among female entrepreneurs. Using convenience sampling, 8 married women entrepreneurs with children from various sectors were selected for semi-structured interviews. Content analysis (Bardin, 2011), units of meaning analysis (Moreira et al., 2005), and Qualitative Synthesis (Major & Savin-Baden, 2010) were employed. The analysis revealed five key categories: “exhaustion,” “family-work conflict,” “lack of support network,” “less suffering from labor conditions,” and “lack of entrepreneurial training.” The most cited category was exhaustion, highlighting the physical and emotional overload from balancing work, family, and entrepreneurial responsibilities, which negatively affects mental health and quality of life. These findings emphasize the significant impact of the triple workday on women entrepreneurs' mental well-being and quality of life, compounded by gender-related challenges and wage disparities. The results underscore the importance of incorporating intersectionality theory when studying these phenomena, as it helps reveal the complex and overlapping nature of the barriers faced by women entrepreneurs. Addressing these issues requires gender-sensitive policies and structural support to promote equity and improve work conditions, particularly for vulnerable or minority women.