This work discusses the technical barriers that exist for the viability and adoption of key technologies for a clean energy supply in Latin America and the Caribbean (LAC), taking into account motivations, constraints and differences between different countries. In the conclusions we highlight the existence of available information about common problems that can be treated in a similar way in different countries to overcome barriers that arise in the energy transition and in this way enhance regional cooperation and energy integration optimizing the use of existing resources to accelerate the transition away from fossil fuels