Introduction: Cervical cancer (CC) is caused in approximately 95% of cases by persistent infection with human papillomavirus (HPV), predominantly transmitted through unprotected sexual contact. This infection leads to alterations in the cell cycle of cervical epithelial cells, potentially resulting in precursor lesions, such as carcinoma in situ — an early and localized stage of the disease — which, if left untreated, may progress to invasive cancer. In the state of Pará, CC is the second most frequent cancer among women, reflecting significant socioeconomic disparities and limited access to healthcare services. In this context, an updated analysis of mortality trends is essential for guiding public health strategies. Objectives: To analyze the epidemiological profile, temporal trends, and geographic distribution of mortality due to carcinoma in situ and invasive cervical cancer in the state of Pará from 2019 to 2023. Methods: This is a retrospective, descriptive, and ecological study based on secondary data extracted from the Mortality Information System (SIM/DATASUS). Deaths related to malignant neoplasms of the cervix (ICD-10: C53) and carcinoma in situ of the cervix (ICD-10: D06) from 2019 to 2023 were analyzed. Variables included total number of deaths, year, municipality, age group, and race/ethnicity. Results: In the period analyzed, 1.912 deaths from malignant neoplasms and carcinoma in situ of the cervix were recorded in Pará, with an average of approximately 382 deaths per year. The year 2022 recorded the highest number of deaths (417; 21.8%) and 2021 the lowest (349; 18.3%). Belém was the municipality with the highest number of deaths (425; 22.2%), while the municipalities with the lowest records (1 death each; 0.05%) were: Abel Figueiredo, Aveiro, Cumaru do Norte, Pau D'Arco, Peixe-Boi, Placas, Santa Luzia do Pará, Santa Maria das Barreiras, and Sapucaia. The most affected age group was 40 to 49 years old (483; 25.3%) and the least affected were 15 to 19 years old (1; 0.05%). The predominant race/ethnicity was brown (1,504; 78.7%) and the least represented was Asian ancestry (6; 0.3%). Conclusion: The temporal analysis revealed a relatively stability in the mortality rate from CC and carcinoma in situ in the state of Pará between 2019 and 2023, highlighting the need to strengthen preventive measures, such as expanding Pap smear test coverage and increasing HPV vaccination rates, in order to reduce these indicators. The persistently high number of cases over the years reinforces the importance of ensuring adequate monitoring and appropriate treatment for patients already diagnosed. The higher mortality rate observed in Belém may reflect its high population density and its role as a regional healthcare hub. The greater impact on brown-skinned women aged 40 to 49 reinforces the urgency of intensifying screening and health promotion actions aimed at this group, identified as being at greater risk.
It is with great enthusiasm that we present the Annals of the Oncology International Symposium 2025, an event that continues to solidify its significance in the oncology landscape of northern Brazil. Held in Belém, Pará, Oncology 2025 centered around the theme "The cancer control challenge: better knowing it to best facing it," dedicating itself to exploring the latest frontiers in cancer treatment and prevention.
This year, the symposium provided a deep dive into the essential role of knowledge in the fight against cancer, presenting new perspectives and scientific advancements across various areas of oncology. Renowned global experts gathered to share their most recent research and innovative approaches, offering participants a comprehensive view of the challenges faced by healthcare professionals and patients worldwide.
Presentations and discussions during the event focused on critical topics such as the use of new technologies, advancements in personalized therapies, and more effective prevention strategies. Additionally, particular attention was given to the unique challenges faced by the Amazon region, with efforts aimed at developing region-specific solutions to meet local needs.
Beyond being a high-caliber academic event, Oncology 2025 stood out as a moment for integration and professional networking, with the warm hospitality of the city of Belém offering participants a unique experience. This event became a platform for exchanging ideas, where science, culture, and humanity came together in pursuit of a common goal: to improve cancer control both in Brazil and globally.
This collection of abstracts and articles presented during the event reflects the ongoing dedication to research and the development of innovative solutions, highlighting the importance of collaboration and shared knowledge in the fight against cancer.
General Submission Guidelines:
The presenting author, who does not have to be the first author, must be registered for Oncology 2025.
Each abstract may have up to 10 authors, including the main author and co-authors.
Only original, unpublished work will be accepted.
Submissions must be related to oncology. However, project descriptions, work proposals, experience reports, and literature reviews will not be considered.
Clinical case reports are allowed, provided the abstract addresses scientific questions, details clinical observations, and includes primary scientific data.
The abstract must be written in English, but presentations may be given in Portuguese.
Abstracts must be between 300 and 500 words.
Comissão Organizadora
Comissão Científica
See Annals of Oncology 2023 at:
https://www.even3.com.br/anais/oncology-2023-international-symposium/
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