EPIDEMIOLOGY OF UTERINE CERVICAL NEOPLASMS IN THE CITY OF BELÉM, PARÁ (2019-2024): REGIONAL CHALLENGES AND CONTROL PERSPECTIVES

  • Author
  • Sayuri Baia Ubagai
  • Co-authors
  • Ana Clarisse Ferreira Rodrigues , Ana Laura Fonteles Santos , Anezito de Lucas Lopes Correa , Karoline Souza Carvalho , Lucas Gabriel Cardoso de Souza , Luiz Antonio Wanzeler da Silva , Naoto da Cunha Hayasaki
  • Abstract
  • Introduction: Cervical cancer (CC) has emerged as an important public health challenge in the North of Brazil, especially due to its high incidence and significant impact on female mortality. The city of Belém, in the state of Pará, reflects a complex epidemiological reality with worrying patterns of hospital morbidity and insufficient adherence to screening strategies, hindering effective prevention and early diagnosis of the neoplasm. Therefore, controlling CC has become a strategic priority for the equitable and comprehensive promotion of women's care. Objectives: To conduct a study on the epidemiological and sociodemographic profile of cervical cancer cases in Belém, Pará between 2019 and 2024, with an emphasis on the aspect of early health screening, based on the cytopathological examination. Methods: This is an ecological, descriptive study with a retrospective approach, based on consolidated statistics on the incidence, hospitalizations, mortality, and cervical cancer screening in the municipality of Belém, Pará, from 2019 to 2024. Data on malignant cervical neoplasia (ICD-10 C53) were obtained from the Department of Information Technology of the Unified Health System, using secondary data from the Cancer Information System and the Mortality Information System. The analysis considered the variables: sex, age group, and self-reported race/skin color, following the classification used by the Brazilian Institute of Geography and Statistics. Results: A total of 117,506 cytopathology tests were performed in Belém during the study period, with 115,947 (98.7%) conducted specifically for cervical cancer screening. Of the total examinations analyzed, 5,208 (4.5%) indicated indicated low-grade squamous intraepithelial lesions (LSIL), and 1,609 (1.4%) showed high-grade squamous intraepithelial lesions (HSIL), which are associated with an increased risk of progression to invasive cervical carcinoma if not adequately treated. Furthermore, 141 cases of squamous cell carcinoma were identified. Hospitalizations for cervical cancer represented 67.3% of total medical admissions in the state of Pará, with the highest number recorded in year of 2024 (592). The majority of hospitalizations occurred among women who self-identified as of mixed race/skin color (2,776 cases; 94.2%), and aged 30 to 59 years  (2,079 cases; 70.5%). Additionally, Belém reported 646 deaths from CC, with a mortality rate of 21.94%. Of these deaths, 613 occurred among women who self-identified as of mixed race. Conclusion: The analyzed epidemiological profile highlights the persistent challenge of elevated mortality rates from cervical cancer in Belém, Pará. The cytopathological tests perfomed and the significant detection of precursor lesions emphasize the relevance of early intervention strategies. However, the considerable number of oncological hospitalizations due to CC reveals weaknesses in the healthcare network and limited access to timely diagnosis and treatment. The data point to a particularly vulnerable group, women of reproductive age who self-identify as of mixed race. The concentration of cases in this racial group was statistically significant, indicating racial and social disparities in disease outcomes. The findings of this study reinforce the urgency of implementing regional public policies that integrate primary prevention, epidemiological surveillance and specialized care. Effective control of cervical cancer thus requires a continuous, territorially based approach focused on health equity in the Northern region.

  • Keywords
  • Epidemiological profile; uterine cervical neoplasms; papillomavirus infections.
  • Modality
  • Pôster
  • Subject Area
  • Case Report or Epidemiology
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It is with great enthusiasm that we present the Annals of the Oncology International Symposium 2025, an event that continues to solidify its significance in the oncology landscape of northern Brazil. Held in Belém, Pará, Oncology 2025 centered around the theme "The cancer control challenge: better knowing it to best facing it," dedicating itself to exploring the latest frontiers in cancer treatment and prevention.

This year, the symposium provided a deep dive into the essential role of knowledge in the fight against cancer, presenting new perspectives and scientific advancements across various areas of oncology. Renowned global experts gathered to share their most recent research and innovative approaches, offering participants a comprehensive view of the challenges faced by healthcare professionals and patients worldwide.

Presentations and discussions during the event focused on critical topics such as the use of new technologies, advancements in personalized therapies, and more effective prevention strategies. Additionally, particular attention was given to the unique challenges faced by the Amazon region, with efforts aimed at developing region-specific solutions to meet local needs.

Beyond being a high-caliber academic event, Oncology 2025 stood out as a moment for integration and professional networking, with the warm hospitality of the city of Belém offering participants a unique experience. This event became a platform for exchanging ideas, where science, culture, and humanity came together in pursuit of a common goal: to improve cancer control both in Brazil and globally.

This collection of abstracts and articles presented during the event reflects the ongoing dedication to research and the development of innovative solutions, highlighting the importance of collaboration and shared knowledge in the fight against cancer.

General Submission Guidelines:

The presenting author, who does not have to be the first author, must be registered for Oncology 2025.
Each abstract may have up to 10 authors, including the main author and co-authors.
Only original, unpublished work will be accepted.
Submissions must be related to oncology. However, project descriptions, work proposals, experience reports, and literature reviews will not be considered.
Clinical case reports are allowed, provided the abstract addresses scientific questions, details clinical observations, and includes primary scientific data.
The abstract must be written in English, but presentations may be given in Portuguese.
Abstracts must be between 300 and 500 words.

  • Molecular Studies
  • Experimental Research or Clinical Research
  • Case Report or Epidemiology
  • Others

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See Annals of Oncology 2023 at:

https://www.even3.com.br/anais/oncology-2023-international-symposium/