Introduction: The high mortality associated with esophageal cancer reflects current weaknesses in access to early diagnosis and specialized treatment, constituting a significant challenge for health equity and effective cancer control in Brazil. In the Northern region, consisting of seven states, a concerning epidemiological reality persists, characterized by the prevalence of risk factors for neoplasia, such as smoking use and chronic alcohol consumption. In this context, regionalized analysis of the Amazonian capitals enables the identification of morbidity patterns and contributes to a better understanding of existing limitations in oncological surveillance and in the continuum of care for individuals with esophageal cancer. Objectives: To conduct a study on the epidemiological, clinical, and sociodemographic profile of esophageal neoplasia cases in the states of Acre, Amapá, Amazonas, Pará, Rondônia, Roraima, and Tocantins, between 2019 and 2024, with a focus on early diagnosis, opportunistic screening, and risk stratification of the population. Methods: This is an ecological, descriptive, cross-sectional and quantitative study, based on consolidated data on the incidence and mortality of esophageal cancer in the Northern Region between 2019 and 2024. Data on Malignant Esophageal Neoplasia (ICD-10 C15) were obtained from the Department of Information Technology of the Unified Health System, using secondary data made available through the Mortality Information System. The analysis considered: sex, age group, and self-reported race/skin color, according to the classification adopted by the Brazilian Institute of Geography and Statistics. Results: During the study period, a total of 3,189 hospital admissions due to malignant esophageal neoplasia were recorded in Northern Brazil. The most affected states were Pará (968; 30.6%), Rondônia (728; 22.8%), and Tocantins (637; 19.9%), while Roraima registered the lowest number (87 hospitalizations). A predominance of cases was observed among male individuals (2,457; 77,04%), those who self-identified as mixed race (2,500; 78.3%), and within the 50 to 79- year age group (1,900; 59.5%). Northern Brazil recorded 591 deaths from esophageal cancer. The highest number occurred in Pará (195; 32.9%), followed by Rondônia (111; 18.7%), and the lowest in Roraima (23 occurrences). Among the deceased, 470 (79.5%) were male and 121 (20.5%) were female. Regarding race/skin color, 467 deaths (79%) occurred among individuals who self-identified as mixed race. The age group with the highest number of deaths was 50 to 69 years (344; 58.2%). Conclusion: The analyzed clinical-epidemiological profile underscores a high burden of esophageal cancer incidence and mortality, particularly concentrated in specific territories and among vulnerable population groups, namely, mixed race men aged 50 to 79 years. The regional disparities identified point to significant gaps in access to early diagnosis and specialized oncological care. It is important, to reduce the incidence of esophageal carcinomas, to implement strategies for opportunistic and early screening at the primary care level, with an emphasis on performing exams such as endoscopy, primarily targeting high-risk populations such as chronic alcoholics, smokers, and patients with progressive dysphagia. Strengthening this comprehensive health network is essential to reduce mortality, improve clinical prognosis, and promote effective cancer control in these territories, in a manner adapted to regional socio-demographic realities.
It is with great enthusiasm that we present the Annals of the Oncology International Symposium 2025, an event that continues to solidify its significance in the oncology landscape of northern Brazil. Held in Belém, Pará, Oncology 2025 centered around the theme "The cancer control challenge: better knowing it to best facing it," dedicating itself to exploring the latest frontiers in cancer treatment and prevention.
This year, the symposium provided a deep dive into the essential role of knowledge in the fight against cancer, presenting new perspectives and scientific advancements across various areas of oncology. Renowned global experts gathered to share their most recent research and innovative approaches, offering participants a comprehensive view of the challenges faced by healthcare professionals and patients worldwide.
Presentations and discussions during the event focused on critical topics such as the use of new technologies, advancements in personalized therapies, and more effective prevention strategies. Additionally, particular attention was given to the unique challenges faced by the Amazon region, with efforts aimed at developing region-specific solutions to meet local needs.
Beyond being a high-caliber academic event, Oncology 2025 stood out as a moment for integration and professional networking, with the warm hospitality of the city of Belém offering participants a unique experience. This event became a platform for exchanging ideas, where science, culture, and humanity came together in pursuit of a common goal: to improve cancer control both in Brazil and globally.
This collection of abstracts and articles presented during the event reflects the ongoing dedication to research and the development of innovative solutions, highlighting the importance of collaboration and shared knowledge in the fight against cancer.
General Submission Guidelines:
The presenting author, who does not have to be the first author, must be registered for Oncology 2025.
Each abstract may have up to 10 authors, including the main author and co-authors.
Only original, unpublished work will be accepted.
Submissions must be related to oncology. However, project descriptions, work proposals, experience reports, and literature reviews will not be considered.
Clinical case reports are allowed, provided the abstract addresses scientific questions, details clinical observations, and includes primary scientific data.
The abstract must be written in English, but presentations may be given in Portuguese.
Abstracts must be between 300 and 500 words.
Comissão Organizadora
Comissão Científica
See Annals of Oncology 2023 at:
https://www.even3.com.br/anais/oncology-2023-international-symposium/
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