MORTALLITY PATTERNS OF MONOCYTIC LEUKEMIA IN THE NORTHEN REGION FROM 2019 TO 2023

  • Author
  • Ana Luiza da Mota Raminho
  • Co-authors
  • Carolina Costa Monteiro , João Victor Souza Rodrigues , Driely Souza santos , Letícia da Silva Cardoso , Suyanne Luyse Souza Meireles , Sérgio Beltrão de Andrade Lima , Danielle Cristinne Azevedo Feio , Symara Rodrigues Antunes
  • Abstract
  • Introduction: Monocytic Leukemia is one of the most common subtypes of Acute Myeloid Leukemia (AML) and is characterized by the abnormal proliferation of monoblasts and promonocytes, leading to pancytopenia, which compromises the production of other blood cells and consequently affects the physiological balance of the body, negatively influencing the survival and mortality profiles of this disease. Furthermore, it is estimated that globally, more than 300,000 people are affected annually, with a survival rate ranging from 25% to 30%, and the incidence is higher in individuals over 60 years old. In Brazil, it is estimated that around 346 new cases of monocytic leukemia occur annually, with approximately 12 cases per year in the Northern Region, and about 3% of deaths.  Objectives: To evaluate the mortality patterns of Monocytic Leukemia in the Northern Region of Brazil from 2019 to 2023. Methods: A descriptive and retrospective epidemiological study on the mortality patterns of monocytic leukemia in the Northern Region, with data extracted from the Mortality Information System (SIM), retrieved via the TABNET portal and made available by DATASUS. The variables included were: ICD-10 Group C93, Northern Region, Federative Unit, Year of Death, Age Group, Gender, Race/Color from 2019 to 2023. Results: During the analyzed period, approximately 10 deaths were reported in the Northern Region, representing a 23% decrease compared to the 13 deaths recorded in the previous five years. The years 2019 and 2022 had the highest number of deaths, with 30% (3/10) of cases each, followed by 2023 with 20% (2/10), and 2020 and 2021 with 10% (1/10) each. Regarding the geographical distribution, the states of Pará and Amapá accounted for 30% (3/10) of the deaths each, followed by Roraima with 20% (2/10), and Rondônia and Tocantins, with 10% (1/10) each. The gender distribution was balanced, with 50% for both male and female, while in terms of race/ethnicity, 40% (4/10) of individuals were mixed-race, 30% (3/10) were white, 20% (2/10) were black, and 10% (1/10) were indigenous, reflecting the region's ethnic diversity. The age groups with the highest mortality rates were those of 40 to 59 years and 60 to 79 years, each accounting for 30% (3/10) of the deaths, followed by the 1 to 9 years age group with 20% (2/10), and lastly, the 30 to 39 years and over 80 years age groups, each with 10% (1/10). Conclusion: The cases of monocytic leukemia were more frequent in Pará and Amapá, with a balanced gender distribution and a predominance of mixed-race individuals. Furthermore, the highest concentration was observed in the 60 to 79-year age group, indicate the necessity of enhancing early diagnosis and ensuring equitable healthcare access across the region.

  • Keywords
  • Epidemiology; hematology; neoplasm.
  • Modality
  • Pôster
  • Subject Area
  • Case Report or Epidemiology
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It is with great enthusiasm that we present the Annals of the Oncology International Symposium 2025, an event that continues to solidify its significance in the oncology landscape of northern Brazil. Held in Belém, Pará, Oncology 2025 centered around the theme "The cancer control challenge: better knowing it to best facing it," dedicating itself to exploring the latest frontiers in cancer treatment and prevention.

This year, the symposium provided a deep dive into the essential role of knowledge in the fight against cancer, presenting new perspectives and scientific advancements across various areas of oncology. Renowned global experts gathered to share their most recent research and innovative approaches, offering participants a comprehensive view of the challenges faced by healthcare professionals and patients worldwide.

Presentations and discussions during the event focused on critical topics such as the use of new technologies, advancements in personalized therapies, and more effective prevention strategies. Additionally, particular attention was given to the unique challenges faced by the Amazon region, with efforts aimed at developing region-specific solutions to meet local needs.

Beyond being a high-caliber academic event, Oncology 2025 stood out as a moment for integration and professional networking, with the warm hospitality of the city of Belém offering participants a unique experience. This event became a platform for exchanging ideas, where science, culture, and humanity came together in pursuit of a common goal: to improve cancer control both in Brazil and globally.

This collection of abstracts and articles presented during the event reflects the ongoing dedication to research and the development of innovative solutions, highlighting the importance of collaboration and shared knowledge in the fight against cancer.

General Submission Guidelines:

The presenting author, who does not have to be the first author, must be registered for Oncology 2025.
Each abstract may have up to 10 authors, including the main author and co-authors.
Only original, unpublished work will be accepted.
Submissions must be related to oncology. However, project descriptions, work proposals, experience reports, and literature reviews will not be considered.
Clinical case reports are allowed, provided the abstract addresses scientific questions, details clinical observations, and includes primary scientific data.
The abstract must be written in English, but presentations may be given in Portuguese.
Abstracts must be between 300 and 500 words.

  • Molecular Studies
  • Experimental Research or Clinical Research
  • Case Report or Epidemiology
  • Others

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See Annals of Oncology 2023 at:

https://www.even3.com.br/anais/oncology-2023-international-symposium/