Introduction: Frantz tumor, or solid pseudopapillary neoplasm (SPN) of the pancreas, is a rare exocrine pancreatic tumor, typically affecting young females between the second and fourth decades of life. It is characterized by indolent growth and low malignant potential, particularly when identified early and surgically resected. Clinical symptoms are often nonspecific and may include abdominal pain, nausea, vomiting, and weight loss. Diagnosis is generally made through imaging techniques such as CT or MRI, followed by histopathological confirmation. Surgical removal remains the primary treatment option and offers favorable outcomes when feasible. Objective: To report a rare case of pancreatic neoplasm diagnosed as a solid pseudopapillary tumor (Frantz tumor) in a patient with atypical demographic and clinical features. Case Report: M.C.P., a 64-year-old male, evangelical, married, and employed as a street cleaner, residing in Ururupu, Maranhão and originally from Belém, Pará, presented with six months of progressive low back pain, later evolving into postprandial colicky epigastric discomfort. He reported an episode of hematemesis and melena two weeks after symptom onset, which led him to seek emergency care. Over the past five months, he also developed pain in the left inguinal region during walking and an infected right foot ulcer related to diabetic neuropathy. His medical history included diabetes mellitus, systemic hypertension, chronic smoking, and alcohol use. Family history was notable for gastric cancer in a sister and a nephew. Physical examination revealed a cachectic patient (BMI 17.1), pale, with pain on deep palpation of the mesogastric region. His performance status was ECOG 3. Abdominal CT showed a heterogeneous mass in the body and tail of the pancreas, with involvement of the celiac trunk, splenic and common hepatic arteries, as well as the splenic and superior mesenteric veins. There was also infiltration into the lesser curvature of the stomach, extending into the gastric lumen, and three heterogeneous hepatic lesions suggestive of metastases. A liver biopsy confirmed the diagnosis of a solid pseudopapillary neoplasm. Given the presence of an active diabetic foot infection, chemotherapy was initially postponed, and the patient was referred to palliative care services. His prognosis remains guarded due to disease extent and comorbidities. Conclusion: Frantz tumor is a rare and often indolent pancreatic neoplasm, more commonly diagnosed in young women. This case stands out due to the patient's age, gender, and significant comorbid conditions. Despite the atypical presentation, a definitive diagnosis was achieved, allowing for the initiation of an individualized treatment plan. The patient began chemotherapy with a favorable initial response, demonstrating the importance of considering SPN in differential diagnoses even in atypical scenarios.
It is with great enthusiasm that we present the Annals of the Oncology International Symposium 2025, an event that continues to solidify its significance in the oncology landscape of northern Brazil. Held in Belém, Pará, Oncology 2025 centered around the theme "The cancer control challenge: better knowing it to best facing it," dedicating itself to exploring the latest frontiers in cancer treatment and prevention.
This year, the symposium provided a deep dive into the essential role of knowledge in the fight against cancer, presenting new perspectives and scientific advancements across various areas of oncology. Renowned global experts gathered to share their most recent research and innovative approaches, offering participants a comprehensive view of the challenges faced by healthcare professionals and patients worldwide.
Presentations and discussions during the event focused on critical topics such as the use of new technologies, advancements in personalized therapies, and more effective prevention strategies. Additionally, particular attention was given to the unique challenges faced by the Amazon region, with efforts aimed at developing region-specific solutions to meet local needs.
Beyond being a high-caliber academic event, Oncology 2025 stood out as a moment for integration and professional networking, with the warm hospitality of the city of Belém offering participants a unique experience. This event became a platform for exchanging ideas, where science, culture, and humanity came together in pursuit of a common goal: to improve cancer control both in Brazil and globally.
This collection of abstracts and articles presented during the event reflects the ongoing dedication to research and the development of innovative solutions, highlighting the importance of collaboration and shared knowledge in the fight against cancer.
General Submission Guidelines:
The presenting author, who does not have to be the first author, must be registered for Oncology 2025.
Each abstract may have up to 10 authors, including the main author and co-authors.
Only original, unpublished work will be accepted.
Submissions must be related to oncology. However, project descriptions, work proposals, experience reports, and literature reviews will not be considered.
Clinical case reports are allowed, provided the abstract addresses scientific questions, details clinical observations, and includes primary scientific data.
The abstract must be written in English, but presentations may be given in Portuguese.
Abstracts must be between 300 and 500 words.
Comissão Organizadora
Comissão Científica
See Annals of Oncology 2023 at:
https://www.even3.com.br/anais/oncology-2023-international-symposium/
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