Introduction: Bladder cancer (BC) is one of the most common neoplasms of the urinary tract and has a multifactorial etiology, involving both environmental and genetic factors. It is characterized by the disordered growth of transitional epithelial cells, which can give rise to tumors with varying degrees of aggressiveness. Studies indicate that the PI3K/AKT/mTOR signaling pathway plays a significant role in the progression of urothelial carcinoma, with its dysregulated activation — caused by PTEN loss of function, increased AKT expression, and PIK3CA mutations — being associated with tumor growth, cell survival, and invasiveness. In Brazil, particularly in the Northern region, urothelial carcinoma has an estimated incidence rate of 0.69 cases per 100,000 inhabitants, ranking 11th in regional cancer incidence. Moreover, the disease predominantly affects males, occurring three times more frequently in men than in women. Objectives: This study aimed to analyze the epidemiological profile of bladder cancer among adults living in the state of Pará, with an emphasis on distribution by sex, age group, and the evolution of cases over the past decade. Methods: This is a retrospective, descriptive, and quantitative study based on secondary data from cases recorded between 2014 and 2024. Information was extracted from the DATASUS Oncology Panel, considering the variables of sex, age group, year of diagnosis, and clinical evolution. The data were organized and tabulated using Microsoft Excel and subjected to descriptive statistical analysis. The results are presented in absolute and relative frequencies. Results: The analysis by age group revealed a higher proportion of cases among individuals aged 60 to 64 years (12.93%). Among men, the age groups of 65 to 69 years and 75 to 79 years showed the highest proportions, each accounting for 25.87% of cases. Among women, the age group with the highest incidence was 55 to 59 years, representing 19.87% of cases. Conclusion: The epidemiological profile of bladder cancer in the state of Pará indicates a predominance among males, particularly in the 65 to 69 and 75 to 79-year age groups. These findings reinforce the importance of implementing screening and early diagnosis strategies targeting the elderly population, especially men. Furthermore, the need for regional public policies that consider the epidemiological specificities of the Amazon region of Pará is highlighted, aiming to promote preventive actions and ensure timely and equitable access to healthcare services.
It is with great enthusiasm that we present the Annals of the Oncology International Symposium 2025, an event that continues to solidify its significance in the oncology landscape of northern Brazil. Held in Belém, Pará, Oncology 2025 centered around the theme "The cancer control challenge: better knowing it to best facing it," dedicating itself to exploring the latest frontiers in cancer treatment and prevention.
This year, the symposium provided a deep dive into the essential role of knowledge in the fight against cancer, presenting new perspectives and scientific advancements across various areas of oncology. Renowned global experts gathered to share their most recent research and innovative approaches, offering participants a comprehensive view of the challenges faced by healthcare professionals and patients worldwide.
Presentations and discussions during the event focused on critical topics such as the use of new technologies, advancements in personalized therapies, and more effective prevention strategies. Additionally, particular attention was given to the unique challenges faced by the Amazon region, with efforts aimed at developing region-specific solutions to meet local needs.
Beyond being a high-caliber academic event, Oncology 2025 stood out as a moment for integration and professional networking, with the warm hospitality of the city of Belém offering participants a unique experience. This event became a platform for exchanging ideas, where science, culture, and humanity came together in pursuit of a common goal: to improve cancer control both in Brazil and globally.
This collection of abstracts and articles presented during the event reflects the ongoing dedication to research and the development of innovative solutions, highlighting the importance of collaboration and shared knowledge in the fight against cancer.
General Submission Guidelines:
The presenting author, who does not have to be the first author, must be registered for Oncology 2025.
Each abstract may have up to 10 authors, including the main author and co-authors.
Only original, unpublished work will be accepted.
Submissions must be related to oncology. However, project descriptions, work proposals, experience reports, and literature reviews will not be considered.
Clinical case reports are allowed, provided the abstract addresses scientific questions, details clinical observations, and includes primary scientific data.
The abstract must be written in English, but presentations may be given in Portuguese.
Abstracts must be between 300 and 500 words.
Comissão Organizadora
Comissão Científica
See Annals of Oncology 2023 at:
https://www.even3.com.br/anais/oncology-2023-international-symposium/
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