Introduction: Brain cancer represents 88% of central nervous system tumors, encompassing a group of highly lethal neoplasms, in which glioblastoma multiforme is the subtype associated with the highest mortality. Globally, there has been an increase in its incidence, especially in developed countries, and its mortality remains high due to current therapeutic limitations. Considering these challenges, analyzing brain cancer mortality trends is essential for assessing the effectiveness of its diagnosis and treatment in Brazil. Objectives: To analyze the trend of brain cancer mortality in Brazil and its regions, from 2013 to 2023. Methods: This is a descriptive, retrospective and quantitative study. Trends in age-adjusted mortality (AAM) were analyzed from 2013 to 2023 in Brazil and its five regions, with mortality data obtained from the National Cancer Institute's (INCA) Online Atlas of Mortality and population data from the Department of Informatics of the Unified Health System (DATASUS). The Average Annual Percentage Change (AAPC) with their respective 95% Confidence Intervals (95%CI) were determined using Joinpoint software, and the trends were classified as upward, stationary or downward. Statistical significance was set at p < 0.05. Results: In the period analyzed, there were 81,439 deaths from brain cancer in Brazil, with the South region accounting for 44.73% of all deaths. The highest AAM was also recorded in the South (4.41), followed by the Center-West (3.62), Southeast (3.43), Northeast (3.15) and North (2.78) regions. The national trend was downward (AAPC: -1.1; 95%CI -1.7; -0.5; p < 0.000001). Similarly, the Midwest (AAPC: -0.9; 95%CI -1.7; -0.1; p < 0.024), North (AAPC: -1.6; 95%CI -2.5; -0.8; p < 0.000001), Southeast (AAPC: -1.3; 95%CI -2.0; -0.7; p < 0.000001) and South (AAPC: -1.1; 95%CI -2.0; -0.2; p < 0.0079) regions showed a downward trend. The trend was stationary only in the Northeast (AAPC: -0.5; 95%CI -1.6; -0.7; p < 0.38). Conclusion: There has thus been a progressive reduction in brain cancer mortality in Brazil between 2013 and 2023. This may reflect recent advancements in neuro-oncology and the subsequent development of new therapeutic techniques, as well an improved access to care. In addition, the downward pattern was evident in most Brazilian regions, except in the Northeast, which registered a stationary trend. However, the number of deaths and the age-adjusted mortality were higher in the South. This possibly indicates an intensification of policies related to the treatment of the disease during the period, focused especially on areas with higher known mortality, associated with an underreporting of cases in the North and Northeast regions. Therefore, there is a need for public health strategies that address regional disparities and ensure equitable access to brain cancer care across Brazil.
It is with great enthusiasm that we present the Annals of the Oncology International Symposium 2025, an event that continues to solidify its significance in the oncology landscape of northern Brazil. Held in Belém, Pará, Oncology 2025 centered around the theme "The cancer control challenge: better knowing it to best facing it," dedicating itself to exploring the latest frontiers in cancer treatment and prevention.
This year, the symposium provided a deep dive into the essential role of knowledge in the fight against cancer, presenting new perspectives and scientific advancements across various areas of oncology. Renowned global experts gathered to share their most recent research and innovative approaches, offering participants a comprehensive view of the challenges faced by healthcare professionals and patients worldwide.
Presentations and discussions during the event focused on critical topics such as the use of new technologies, advancements in personalized therapies, and more effective prevention strategies. Additionally, particular attention was given to the unique challenges faced by the Amazon region, with efforts aimed at developing region-specific solutions to meet local needs.
Beyond being a high-caliber academic event, Oncology 2025 stood out as a moment for integration and professional networking, with the warm hospitality of the city of Belém offering participants a unique experience. This event became a platform for exchanging ideas, where science, culture, and humanity came together in pursuit of a common goal: to improve cancer control both in Brazil and globally.
This collection of abstracts and articles presented during the event reflects the ongoing dedication to research and the development of innovative solutions, highlighting the importance of collaboration and shared knowledge in the fight against cancer.
General Submission Guidelines:
The presenting author, who does not have to be the first author, must be registered for Oncology 2025.
Each abstract may have up to 10 authors, including the main author and co-authors.
Only original, unpublished work will be accepted.
Submissions must be related to oncology. However, project descriptions, work proposals, experience reports, and literature reviews will not be considered.
Clinical case reports are allowed, provided the abstract addresses scientific questions, details clinical observations, and includes primary scientific data.
The abstract must be written in English, but presentations may be given in Portuguese.
Abstracts must be between 300 and 500 words.
Comissão Organizadora
Comissão Científica
See Annals of Oncology 2023 at:
https://www.even3.com.br/anais/oncology-2023-international-symposium/
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