First-line tandem high-dose chemotherapy and autologous stem cell transplantation versus single high-dose chemotherapy and autologous stem cell transplantation in multiple myeloma, a systematic review of controlled studies

Frauke Naumann-Winter, Alexander Greb, Peter Borchmann, Julia Bohlius, Andreas Engert, Roland Schnell

Several clinical studies have compared single with tandem (also called double) autologous stem cell transplantation (ASCT) as first-line treatment in patients with symptomatic multiple myeloma (MM), one of the leading indications for ASCT worldwide.

The present Cochrane Review compares tandem autologous stem celltransplantation (TASCT) with single autologous stem celltransplantation (SASCT) as first-line treatmentin patients with symptomatic MM with respectto overall survival (OS), event-free survival (EFS), quality of life (QoL) and treatment- or transplantation-related mortality.

Confira a íntegra do artigo aqui. https://lnkd.in/dFqqtgY

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